Serrapeptase: Understanding The Miracle

When I wrote that:

I want to understand the processes by which a proteolytic enzyme, Serrapeptase, started and sustained, what I am certain is a life-saving cascade of changes, by which I have returned to and surpassed the good health I once enjoyed.

I received more e-mails and questions than I have for a very long time. Most people were asking why, if I am happy to describe Serrapeptase as The ‘Miracle’ Enzyme, I am so determined to understand how it works, what its impact has been and, more interestingly, what its potential may be.

I am in no doubt that Serrapeptase is deserving of its title, given to it by Robert Redfern, The Serrapeptase Guy, who renamed his book: The ‘Miracle’ Enzyme Is Serrapeptase, after hearing of My Serrapeptase Adventure in 2006 and included my remarkable return to good health in the 2009 edition.

The assumption that many people seem to be making is that to define something as a miracle, one must suspend the powers of reason and critical thinking. I do not agree.

Consider the awe-inspiring beauty of a sunset. I understand how the visible colours are produced by light, refracted by atmospheric conditions and the angle of the sun, compared with my position on the surface of the earth. Despite this rudimentary understanding of physics, I am inspired by every sunset I see. In the years before my return to health, I was able to enjoy the beauty of sunsets, even when my eyesight was at its weakest. Now that my sight is so much better and I can see small details, beauty on such a massive scale still inspires me. The miracle, for me, is not how the colours are created, but that they have such an effect upon me.

I am convinced that the better I understand Serrapeptase, the more I will see that it is The ‘Miracle’ Enzyme. The first time I took Serrapeptase, my only hope was that it would be an effective painkiller. Within a matter of days, I was learning by joyful personal experience, that it had started a cascade of improvements in my health that I believe saved my life. My Serrapeptase Adventure has freed me from the ‘toxic cocktail’ of prescription medication. I continue to be free of chronic pain, my lung and heart conditions have disappeared, and my eyesight and visual perception have improved beyond anything I could have imagined. Neither I nor anyone who knew me at that time expected or understood that a single enzyme could have such a life-changing impact. I cannot think of a better description of a miracle.

Serrapeptase was discovered in the early 1970s and it is now in extensive clinical use throughout Europe and Asia as a viable alternative to salicylates, ibuprofen (sold as an OTC in the USA.) and the more potent NSAIDs. Serrapeptase is an anti-inflammatory, proteolytic enzyme isolated from the micro-organism, Serratia E15 and has no inhibitory effects on prostaglandins, is devoid of gastrointestinal side effects and offers a sensible alternative.

This immunologically active enzyme is completely bound to the alpha 2 macroglobulin in biological fluids. Histological studies reveal powerful anti-inflammatory effects of this naturally occurring enzyme. The silkworm has a special relationship with the Serratia E15 micro-organisms in its intestines. The enzymes secreted by the bacteria in silkworm intestines can dissolve avital tissue but have no detrimental effect on the host’s living cells. Thus by dissolving the silkworm’s protective cocoon (avital tissue), the winged creature is able to emerge and fly away.

The mechanisms of action of Serrapeptase, at the sites of various inflammatory processes, consist fundamentally of a reduction of the exudative phenomena and an inhibition of the release of the inflammatory mediators. This peptidase induces fragmentation of fibrinous aggregates and reduces the viscosity of exudates, thus facilitating drainage of these products of the inflammatory response and thereby promoting the tissue repair process. Studies suggest that Serrapeptase has a modulatory effect on specific acute phase proteins that are involved in the inflammatory process.

Although my recovery is a fantastic gift, my improved eyesight and still improving visual perception is different. My eyesight was impaired from birth, as a direct result of the congenital impact of cerebral palsy. This means that improvements in my sight, and particularly in my visual perception, represent the development of new abilities that are even more remarkable than the recovery of old ones.

Does this mean that the remarkable enzyme, Serrapeptase, can overcome the impact of congenital brain damage? There is now some research, based upon studies of newborns, suggesting that inflammation may be amongst the underlying causes of cerebral palsy. One indicator for this was the elevated level of inflammatory cytokines. I am not yet sure that it is possible to extrapolate from this that reducing the level of inflammation in adulthood, could help to mediate the effect of congenital damage, but am sure that it is a question worth asking\ and that the answer will be a fascinating one to find.

I believe that miracles are given to us as gifts. They are not to be passively accepted, but they provide unexpected opportunities to gain new understanding. It is for this reason that I am sure that Serrapeptase is The ‘Miracle’ Enzyme and that I can look forward to understanding the miracle.


In July 2006, Robert informed me that, having learnt of my experience of using Serrapeptase in the management and reduction of the impact of my Cerebral Palsy (CP) symptoms, he had renamed his book as The ‘Miracle’ Enzyme is Serrapeptase.

Since the 2009 edition, the book has included a section called The Mike Tawse Story – From Wheelchair To Wings. I would like to take this, and every opportunity to thank Robert Redfern for the privilege of sharing My Serrapeptase Adventure with the world.

The newest edition of The ‘Miracle’ Enzyme Is Serrapeptase was released in 2018.

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Joan Lulich

Calling it a “Miracle” makes many people wary of the product. People are programmed to believe that there is no such thing and that it is only a marketing ploy. These are people whose only recourse, they believe, is surgery. Unfortunately, the adjective backfires.

Mike Tawse: The Health-Care Survivor

Hi Joan — Thank you for your comment, and for raising this important issue. I must admit that when I first heard people describing My Serrapeptase Adventure, and then Serrapeptase itself, as a ‘miracle’, I was concerned. At the time, in the summer of 2006, it was not at all certain to me that my improving health would be sustainable. I was thrilled that other people were so confident, but it took me some time to begin to agree with them.

Now, I am in no doubt at all that my return to health, and therefore, Serrapeptase, represents a miracle. For me, the miracle of Serrapeptase is that it stabilised, and then improved my condition to such an extent that I was freed from the toxic cocktail of prescription medication, to which I have never needed to return. It also taught me the most valuable lesson of all: health is the body’s natural state, even when one has a permanent and irreversible underlying condition, like cerebral palsy.

To be absolutely clear, I still have cerebral palsy. Serrapeptase has not removed, or cured the condition, but it has improved my health to such an extent that I have returned to the cerebral palsy of my childhood. It was then, and is now, a daily challenge to be managed and overcome. Cerebral palsy is no-longer the condition, dominating my life, which it had become in the decade prior to the start of My Serrapeptase Adventure, in 2006. Most importantly, I remain free of the toxic cocktail of prescription medication, which I believe damaged my health and quality of life, far more than cerebral palsy ever has done, or is ever likely to do.

Life remains a challenge, but it is one to be met, welcomed and overcome.

David Meyer

The term ‘miracle’ is subjective and is certainly overused in the advertising business. A miracle whitener for teeth or a miracle polish for your car. So why would it be used for a simple enzyme?

Having known Mike since the start of his journey to good health, I can certainly understand why he and many others have described it as a miracle, even though we understand a lot of how it works. As a full time Health Coach, I talk to many people who have believed that their doctor knows everything and if he says there is nothing that can be done for their condition, then they just have to accept it.. When they are persuaded, usually by a good friend, to try Serrapeptase and their condition improves, or even fully resolves, then they cannot believe it is anything other than a ‘miracle’

Perhaps the biggest ‘miracle’ is that people in dire need of help get to hear of Serrapeptase, despite the efforts of ‘Big Pharma’ to suppress it.

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